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Apr 6, 2021 · The flexibility of replisomes coupled with tolerance and repair mechanisms counteract these replication fork obstacles.
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Apr 22, 2023 · Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, ...
Definition. Enzyme that catalyzes DNA synthesis by addition of deoxyribonucleotide units to a DNA chain using DNA as a template. · Category. Molecular function.
Resulting ssDNA overhangs are then coated by the ssDNA-binding complex RPA (replication protein A) before being substituted by RAD51 proteins with the help of ...
Mar 12, 2024 · We find that ZNF827 accumulates at stalled forks and DNA damage sites, where it activates ATR and promotes the engagement of homologous ...
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of ...
Nov 19, 2021 · The work of DNA ligase is to form "phospho-ester bond" or "phospho-diester bond"(bond joining phosphate of one nucleotide with OH of another ...
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of ...
DNA-directed DNA Polymerase - an overview | ScienceDirect Topics
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TP affects DNA replication directly by changing the structure of linked original DNA and stabilizing the binding of pTP adeno polymerase heterodimer to its ...
Mar 7, 2014 · DNA replication in the 5' to 3' direction is a process that involves the unwinding of the double helix structure of DNA and the addition of new ...